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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5648ef5a497bf7c4fb11f2a045d962f61b397825d69e1ec82e8acccc6b09fd14' 
  AND token = 'Wq4LkoUuIv80T36bSqqKJahYkJnfy8dgArrUs9GiM9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}