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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '848e0c2a4b0a20341e541e9ce2bc854a73e04b8167038fb2dad9b03f670907a5' 
  AND token = 'Oql1IAobzVUGt/OajhtDm/Rjpqz/Ahk7/mS5Oi/kUCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}