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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e1b987b3c97e6c1448e3b79a5a96b20dd0cede54d1f2a3ec33e0895fb66a01' 
  AND token = 'lfT4wTNBTskpE7gx65s43VCym0iq4ewm1RH+X5cHr1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}