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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69afa08cd46b41efe560c421a0d2d1fb23a49e82206bb4e7b3b88cc2b6a16876' 
  AND token = '+tLnt9BIGt4fs3JdKVpGtnBA8oWiAffQENhCpNg9R48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}