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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ffd3cb830d9381fbd03b506e3e7bf5dc5a4bf1681e911934c26ff3d7aaa3a22' 
  AND token = 'Gyv+sYKRGL2FFfkagCIXZSSMboiioTax3MLyvMqVSrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}