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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '839a11e855c7d8fa2b38f687b84c6bc1182fd429414da4cc8a32481249574f90' 
  AND token = '1myStB+4WUUrbIJ+HQrfZPLiD2bQ/JHMHozTcrJmnf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}