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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4477a52063e2fd6a5f15925704260c6f80cc1b41435313c7874cf5dbc8149089' 
  AND token = 'yzq1GC3cYEUwmydV2oM+h7XeTqXLFKaeMjhh3Faah6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}