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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7bfd77780abc04bf949b8a71f9bb596d342a2447f5973935212fa023ffefad9' 
  AND token = 'IA/fj911Zo+J5d+7gW9xRdMzhJktXaqDLjKi7nt67ZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}