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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f6542a39c206c8d7020a036f2dc13647353399b95ad6c5f89fe63d7ff88304b' 
  AND token = 's9sDhdL6nbrF1T8bH36UXXcSHyGwO7OGipACBlx1E0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}