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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4e63021013f12e0abc5f025e8cf3d3fc5a2dc3c72695195e94476d7e14ad107' 
  AND token = 'e+OKF+rkz+RXp2HhdMRLNcOy1OHwyV1XXTtK4TnxyHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}