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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a9cbba25adbb8706f48e39414f4612f29509fae72ed32eeeed2fc21dbe139be' 
  AND token = 'BOUW9aW3IZFIrZRIJyxdiaDsVAElG78c1No1huXx/6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}