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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a04b8c221c48b15789acc256950dfaa279d21a5c9d8bdca8dcf75a98bf63bc13' 
  AND token = 'fboS03aTIFyLqpgW22xZxBU0t8CHk0qCjHJkjvsYSUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}