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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a716dec487ab09da7d1a116235403de976be115d7971e3aaef9ef9aeb2b026d2' 
  AND token = 'zfKUhlS69LNfN6BPC05UrpIQ/w2RQCQ1swW2MUgQyaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}