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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '539cfc6510b44b3efccdb1f66dd50a175a2fff9a0b5a61792dd2c6c4367a2995' 
  AND token = 'hOqY0flQPtWyMxiJ3MzgndPDBRw6/x72VuwzE9boyrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}