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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef0524447edb4e2d55bee6ef078399e35ffd6326078ceb4b856e47e290966b53' 
  AND token = '2dOpTQea4YfTjkmunWaONOzT6xcev2I9/HdGJjeqLOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}