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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6003b20febb3523ecdd2a2033d2685e1b0597d9ea245a6b204ad8422f9e9d4e' 
  AND token = 'IMVlh/590hV27Lx12RunpYnxcc0E9XR4eJ9VmxVTB8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}