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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e09c9d4dfd2c180277e4b9996621eee376bdab463b501223716d64d2e41c9dea' 
  AND token = 'ixTzeV4j+VJ8u5tozgZAitHmThdGT/rEMYcAP99pcoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}