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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50e6ac84ce29538338bf92fc3e255d61efed3eb62de58e671a0944fccd37e3ca' 
  AND token = 'Wr4hIxOmy/K19qD8tiRbyA9Qdaq99aGAHtg1lHTe9kc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}