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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a317a2ff3dfef2afbb8e5306e93f9767da2b7c8f471e8978acc355f6b2ab252b' 
  AND token = '8DOaKga7K8hSzqrcaFzDvnpXbzNnmGLLLFBDVsE7Vfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}