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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5a31918e748dbc55561aa8bbd9a490888b50b7a8a5168526ab0ad67a74a5b86' 
  AND token = 'ixWec1OvF2zljX76zheCgjDJdcKjaiO6rJoz1uZCVbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}