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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7dfb544624837c8887c4293c1c090c3daf1ca8a610a63c78c6b4392eee8390e0' 
  AND token = 'UzYMADMmo2fT1HAU3cU5OzNdYA57u6wpCK2MvVoxsmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}