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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cb025e7ff46e36e527a187667849fb912fc6d5cca8058638af52e57bfdc0485' 
  AND token = '4XeyTNG6BwFO9DgkOioAprn8mKWsV0PGAetY7wJoudg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}