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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0541f4b5783e06a2b3b448b843a2116a4bbdedd7c8e27be4615f1d981d3f133' 
  AND token = 'fha/ErB4roLenOiQ63eBUkP2jx8KnV35CIkHDxUhYps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}