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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f067b3e153f3e9544722a0da3c3529d61a5d09f4d59d191d1ee46d4f6fefebe' 
  AND token = 'NiGy5JoMgN/mr1j5EyOekiGbYDBWCyn6CVs8+EvXAtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}