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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b47247b31f16207d220e48ba020c5f0ece9d222ce825999f3bd86ef391fbf325' 
  AND token = 'NIaSrd1nEvgJxztu9zXl4L5E+AUK/3AiR4x5N5uYBw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}