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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fedf622b25b3f71f594fb1270a0079c089e4d319038c900e8fc232f27096704a' 
  AND token = 'YI6vRFxDTB2fiE4Kit+cyPEoc/5JyeCuG6IK/rtBkOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}