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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf2816c60567f2b1ccb21aa9888d62dd5debcbe4498876cefef65a1bf3a8b561' 
  AND token = 'ZVNI5L1xQf0RsRzenB/1YQebRTgX13EMRMlGOXVhHL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}