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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2708f4d18b45707594f3e4f87f6c69122fb47b812280f49e8dd12b746e068417' 
  AND token = 'NFfH4Yidge75e9RAunUhWTj0b9qHsvBx5B59KXsJK8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}