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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1c17c88b5c1f4dde35f8cd845b9cf52d1fa2823a8e14da964157c714179a0f9' 
  AND token = 'Giy1UakWRryLkR9sMgnjgtdA5sh3c7bHzzgJLO4G1GQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}