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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04e706c5b67732ee34fe05ad9abd04aed54ce082ac1f1375d0b9de9b094cd157' 
  AND token = 'WHRv+Gsn0F3oiHiDv3cFNwvzdsD8qcKF8pU+Jos5cIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}