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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '596e44fe7d2b16664b6b8f83c1f84f1031130901862c86a9f87ac967255efa2f' 
  AND token = 'GF2b7XzP3aI7I0LvmT571Xi3KpbyY2TJqHyMe5Iy4Qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}