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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '051378bdc4efe2bc8540e78d532396b56fecc1bb3bdbf5bed9ec92a41d3dc781' 
  AND token = 'VJxWq+UZesrM/KRc7yaosHOQXypeze4rYmu+egAq6I8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}