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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c10f8ecb9da9367815f1979a23074e72104276f39bd7584b95b6eb20e039fe40' 
  AND token = '76YON3eRzgoyxmO/I26IpwMIas3prETj76vMPRs5qn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}