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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a734bf68646dd48400cbd2e296bdeb2eedeaf7a4a1b800a8359270281ab93424' 
  AND token = 'NX2PDHXtSqm+irLyBElKtZC5tBcbXeUcdlQeYXJ+Q9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}