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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '121c14211621e7ab6ac4fc79644456adbe10f1737ecb6be8e5c42dffa353798d' 
  AND token = 'A9DZCdTLfevtS7/koYXNuCEBy7jPXcp5w8XBsYqd+l4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}