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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0edfb053bbb52e9737fdd6a51e41b69bdc052f1957ebae718b88b33c05e4fb7b' 
  AND token = 'bPcwVizX68KPQKBCS73d+8Tgaswo7uyEk4TRp7H23fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}