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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca65a0e3baa5e77b58e7705bb786cb578d75bf916990c8c9f05e96efc137ad2e' 
  AND token = 'FISeeQ0/NobKv48hQ0vtMWq97kBssWk0SaIwm1nKreU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}