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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd38731e364f5d3ec3a73d6854961310959bcaa8c70320f522b8c7cfe7efbc220' 
  AND token = 'p1JbMUWufTRMb+JBMMqfVF93JFW+ub6cZ6iMgfjgEUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}