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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d6bb19adc4afd859d6e1cf4cf904a1bf45a55315b7912503b3c26e214d5c4b0' 
  AND token = 'yLRpVz1lWsLLbw8auDV8PA+F3c7Ck8IApYg/ObAuPik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}