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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9a644849b4e3869cc153753d3a596e52a9d26482ef3443f27d0862d59ee0f10' 
  AND token = 'hP5vLCeYLZYkEyDWT1dUNBCz0xEb4Da7kx+J6mWVm3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}