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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fa2ebce6aa879dce4e9f7dbd12cf07da722d86de1ece76add58bbed1fbcf916' 
  AND token = '4jCvEX5mcv0dxYO4F8BlvXrygyj9ZtJpfPW3QV2TRx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}