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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f81f58dedc801974e501a4aa06bef144b85ed8bd25ce51fcb8dbf8d42379ab24' 
  AND token = 'lVmKY6gEDgjn7n+qk6Wc868Ie4ztBiyeuVRh76mItHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}