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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '887489b2fb78c9696cd73f1747b1d072cfa1646bf8e3beaa8b6c1bc87c347d0b' 
  AND token = 'm2DSMJiTaOAm3PPUJpEUh9k3Noq6ijZBPJRLO2c/X5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}