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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '406cd1d1d8f0e6c56496772d287e39bdf61b7c5153dedb4f1adc99e4665a434f' 
  AND token = 'NKX04fHePUuzjX0/o6+y/3b6RoZL5Qw7TnVoEbfqAes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}