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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f74cb511de8ab8a3a5121a8042b4b889cf2de33d9b24b616f5c40e0984663e29' 
  AND token = 'K+ikr6LR9Wlxbb2NhTpH9uC8BIppVm0o8A6X5ZNusyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}