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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9199fc58faa79fe8a3e09ce9a9a874e17d31415f9a304d8c55f749bcbdc0449' 
  AND token = 'yIMOnJv/VXhlVHIQ0Iz9fXj223YLKcFIrch4nRXUQvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}