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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4cce438a8c707981a0e4ce7140cd620858a567ae329c138157d1e0ee4196431' 
  AND token = '/RcirvJ+059cATdiBeDN5bwAqb3gS/Ks1ouEAtA5Xfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}