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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01f0306e2c57ca2871730760da86ac26210efe5a598b80bd4c0323317e22bb14' 
  AND token = '+7DW33nqY1XDz8S9/rz4tIeH/hqFV96vc9k3WZGkIGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}