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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fef3deb2ac30cd1738e52f4c6baa2389f5678da86e1e280fd40dec1b6e302088' 
  AND token = 'dsUaBPatOUf7rHoIFpJYif2Qwb75G4qXVpjM7Xfb1HQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}