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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2857831547cea29e918c770deb41d7f6c53a1398a08179f7998a8f07e000115a' 
  AND token = '4KMQNrQwOBLnnN/c7UKiGN2wb7V1TBa87Xvy4O0C1z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}